Generic azithromycin 250mg pills


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What Is Azithromycin Used For?

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Product Detail. Neisseria gonorrhoeae is normally susceptible to azithromycin, [21] but the drug is not widely used as monotherapy due to a low barrier to resistance development.

No harm has been found with use during pregnancy. Safety of the medication during breastfeeding is unclear. It was reported that because only low levels are found in breast milk and the medication has also been used in young children, it is unlikely that breastfed infants would suffer adverse effects.

Azithromycin appears to be effective in the treatment of COPD through its suppression of inflammatory processes. Nervousness, skin reactions, and anaphylaxis have been reported. Hearing loss has been reported. Occasionally, people have developed cholestatic hepatitis or delirium. Accidental intravenous overdose in an infant caused severe heart block , resulting in residual encephalopathy.

How should this medicine be used?

In the FDA issued a warning that azithromycin "can cause abnormal changes in the electrical activity of the heart that may lead to a potentially fatal irregular heart rhythm. The warning indicated people with preexisting conditions are at particular risk, such as those with QT interval prolongation, low blood levels of potassium or magnesium, a slower than normal heart rate, or those who use certain drugs to treat abnormal heart rhythms.

Azithromycin prevents bacteria from growing by interfering with their protein synthesis. It binds to the 50S subunit of the bacterial ribosome , thus inhibiting translation of mRNA. Nucleic acid synthesis is not affected.

What is azithromycin?

is used to treat a wide variety of bacterial infections. It is a macrolide-type antibiotic. It works by stopping the growth of bacteria. This. Azithromycin. Generic Name: azithromycin (a ZITH roe MYE sin) Brand Names: Azasite, Azithromycin 3 Day Dose Pack.

Azithromycin is an acid-stable antibiotic, so it can be taken orally with no need of protection from gastric acids. It is readily absorbed, but absorption is greater on an empty stomach. Time to peak concentration T max in adults is 2.

FDA warns of fatal "Z-Pack" side effect

Due to its high concentration in phagocytes , azithromycin is actively transported to the site of infection. During active phagocytosis, large concentrations are released. The concentration of azithromycin in the tissues can be over 50 times higher than in plasma due to ion trapping and its high lipid solubility.

Important information

May Rhabdomyolysis has occurred rarely in patients receiving lovastatin, and some evidence suggests that concomitant administration of erythromycin may increase the risk of this adverse effect. It inhibits some Gram-positive bacteria, some Gram-negative bacteria, and many atypical bacteria. In adults with human immunodeficiency virus HIV infection receiving long-term therapy with oral azithromycin mg daily combined with oral ethambutol for the treatment of Mycobacterium avium complex MAC infection, the discontinuance rate was 9. Safety and efficacy of a single-dose azithromycin regimen for the treatment of acute bacterial maxillary sinusitis were evaluated in a randomized, double-blind study in adults.

In , Pliva and Pfizer signed a licensing agreement, which gave Pfizer exclusive rights for the sale of azithromycin in Western Europe and the United States. Pliva put its azithromycin on the market in Central and Eastern Europe under the brand name Sumamed in Pfizer launched azithromycin under Pliva's license in other markets under the brand name Zithromax in It is available as a generic medication. Azithromycin is commonly administered in film-coated tablet, capsule, oral suspension , intravenous injection , granules for suspension in sachet , and ophthalmic solution.

From Wikipedia, the free encyclopedia. IUPAC name. Interactive image. Brand name listings. Retrieved 24 December Archived from the original on 28 February Retrieved 27 February Archived from the original on 5 September Retrieved 1 August Retrieved 4 September Oxford: Oxford University Press. Archived from the original on 5 March Robin Analogue-based Drug Discovery.

World Health Organization model list of essential medicines: 21st list Geneva: World Health Organization. Critically important antimicrobials for human medicine 6th revision ed. International Drug Price Indicator Guide. Centers for Medicare and Medicaid Services. Retrieved 24 May Retrieved 22 December Archived from the original on 1 March